“断奶安”防治仔猪腹泻的作用机理及应用研究

目的]探讨微生物制剂“断奶安”对仔猪腹泻的防治作用机理。方法]给断乳仔猪口服“断奶安”，观察其对仔猪腹泻率、生产性能、肠道微生物区系、各肠段pH值及肠黏膜形态结构等方面的影响。结果]“断奶安”可提高断乳仔猪的存活率，使腹泻率下降19．24％，且能显著提高断奶仔猪的日增重、日采食量，具有较好的提高断乳仔猪生长速率的趋势及阶段增重优势，使仔猪生长性能得到较高水平的发挥；可通过增强仔猪肠道抵抗力来维持肠道黏膜的机械屏障作用和正常的消化功能，进而提高肠道的黏膜免疫水平；还可通过降低肠道内潜在致病茵比例及其对宿主的毒害作用，使断奶仔猪肠道菌群在极短的时期过渡至并维持在动态平衡状态，并具有降低仔猪肠道内容物pH值的趋势。结论]“断奶安”可有效防治断奶仔猪腹泻。

Research on Function Mechanism and Application of DUAN-NAI-AN on Controlling Weaned Piglet Diarrhea

Objective] The study aimed to explore the function mechanism of microbial ecological agent DUAN-NAI-AN on controlling weaned piglet diarrhea.Method] DUAN-NAI-AN was given to the weaned piglets by oral administration and then its effects on diarrhea rate,growth performance,intestinal microflora,pH values of different parts of the intestine and intestinal mucosal morphology were observed.Result] DUAN-NAI-AN could improve the growth performance of weaned piglets by increasing the growth rate and phase weight gain,showing as higher livability,average daily gain and daily feed intake as well as lower diarrhea rate with 19.24% decline by contrast to the control.In addition,DUAN-NAI-AN could keep the intestinal mucosal mechanical barrier and normal digestive functions by strengthening intestinal resistance and thus enhance the intestinal mucosal immune level.It could also decrease the proportion of potential pathogens and their toxicity effects inside the intestine to help the piglets transfer to and then maintain the dynamic balance of intestinal microflora in a very short period,and it also had a trend to decrease the pH value of piglet intestinal contents.Conclusion] DUAN-NAI-AN is an effective microbial ecological agent for the control of weaned piglet diarrhea.