Nasal Mucosal Adenocarcinoma in a Pet Rabbit |
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| Institution: | 1. Avian and Exotic Animal Clinic, Indianapolis, IN USA;2. Zoo/Exotic Pathology Service, West Sacramento, CA USA.;1. Clinica Veterinaria S. Siro, Milano, Italy;2. Clinica Veterinaria Gran Sasso, Milano, Italy;1. Angell Animal Medical Center, Boston, MA USA;2. Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA USA;3. Brookline, MA USA;4. Center for Animal Referral and Emergency Services, Langhorne, PA USA;1. Department of Zoological Companion Animal Medicine, Cummings School of Veterinary Medicine at Tufts University, 200 Westboro Road, North Grafton, MA 01536, USA;2. Department of Comparative Medicine, University of Washington School of Medicine, 1959 Northeast Pacific Street, Seattle, WA 98195, USA;3. Center for Animal Referral and Emergency Services, 2010 Cabot Boulevard, Langhorne, PA 19047, USA;1. Department of Veterinary Clinical Medicine, University of Illinois College of Veterinary Medicine, Urbana, IL USA;2. San Diego Zoo, San Diego, CA USA;1. Clinic of Small Animal Surgery and Reproduction, Center for Clinical Veterinary Medicine, Faculty of Veterinary Medicine, Ludwig Maximilian University, Munich, Germany;2. Institute of Veterinary Pathology, Ludwig Maximilians University, Munich, Germany;3. Institute of Veterinary Anatomy, University of Munich, Munich, Germany |
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| Abstract: | A 6-year-old male rabbit (Oryctolagus cuniculus) presented with upper respiratory disease that was nonresponsive to antibiotic therapy. Computed tomography revealed a severe space-occupying lesion of the right nasal cavity, deviation of the nasal septum to the left, and narrowing of the left nasal cavity. An exploratory rhinostomy was performed for the purposes of diagnostic sample collection and to improve airflow as clinical signs of dyspnea were becoming more pronounced. The histopathologic disease diagnosis from the biopsy samples was nasal mucosal adenocarcinoma. Palliative rhinostomy provided only temporary improvement in airflow, and the patient was euthanized 3 days later. On necropsy, neoplasia was found to extend into the rhinopharynx. This is the first reported case of nasal mucosal adenocarcinoma in rabbits. This important differential diagnosis should be considered for any rabbit with clinical signs of upper respiratory disease that is nonresponsive to medical therapy. |
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| Keywords: | dyspnea mucosal adenocarcinoma neoplasia rabbit rhinostomy |
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