Electron microscopy of bursa of Fabricius of chicks infected with a field strain of infectious bursal disease virus |
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Authors: | A S Panisup B Jrplid K C Verma G C Mohanty |
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Institution: | 117.Division of Avian Diseases, Indian Veterinary Research Institute, Izatnagar, India ;217.Department of Pathology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, P. O. Box 7028, S-750 07, Uppsala, Sweden |
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Abstract: | Chicks were infected in the bursa with a field strain of infectious bursal disease virus. Inter- and intracellular edema, condensation and margination of nuclear chromatin, increased number of lysosomes in macrophages, and lymphocytolytic changes appeared earliest by 8 hours post infection. Inclusions containing spheroid to hexagonal virus particles were seen in the cytoplasm of the macrophages. Multiplying virus particles in crystalline arrays arranged either in single or in multiple clusters were seen in the cytoplasm of macrophages, lymphocytes and light stained reticular epithelial cells. |
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Keywords: | gumboro disease viral inclusions viral multiplication |
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