Synthesis and antifeedant activity of new oxadiazolyl 3(2H)-pyridazinones |
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Authors: | Cao Song Qian Xuhong Song Gonghua Chai Bing Jiang Zhisheng |
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Institution: | Institute of Pesticides and Pharmaceuticals, East China University of Science and Technology, P.O. Box 544, 130 Meilong Road, Shanghai 200237, P. R. China. |
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Abstract: | A total of 20 new compounds containing the oxadiazolyl 3(2H)-pyridazinone moiety were synthesized. The structures of all the compounds were confirmed by (1)H NMR, IR, MS, and elemental analysis. Their insect antifeedant activities against Asiatic corn borer Ostrinia furnacalis (Guenee) were examined and compared with commercial azadirachtin. The compounds exhibited significant levels of activity. The feeding deterrency values of IIIa,j were 57% and 51% at 500 mg/kg concentration, respectively. |
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