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H10N8亚型禽流感病毒的研究进展
引用本文:谭伟,谢芝勋. H10N8亚型禽流感病毒的研究进展[J]. 中国畜牧兽医, 2014, 41(8): 236-241
作者姓名:谭伟  谢芝勋
作者单位:广西壮族自治区兽医研究所,广西畜禽疫苗新技术重点实验室,广西南宁 530001
基金项目:广西特聘专家专项基金(2011B020);广西科技重大专项 (1222003-2-4)。
摘    要:中国于2013年底首次发现H10N8亚型禽流感病毒(AIV)能感染人并致死的病例,而在此之前从未有过关于H10N8亚型病毒能感染人的报道,目前也未在其他国家监测到H10N8亚型AIV感染人的病例。与H7N9亚型AIV相似,H10N8亚型AIV在家禽中致病性很弱,可一旦感染人能表现出很强的致病性。感染了H10N8亚型AIV的患者病情恶化快、死亡率高、对人的健康危害很大,但至今尚无有效的防制手段。目前还不太清楚H10N8亚型AIV是通过何种途径传播给人的,今后H10N8亚型AIV是否会在人群中引发新的疫情暴发是人们普遍关心的问题。文章简要介绍了H10N8亚型AIV的特点及研究现状。


Research Progress on Avian Influenza A Virus Subtype H10N8
TAN Wei,XIE Zhi-xun. Research Progress on Avian Influenza A Virus Subtype H10N8[J]. China Animal Husbandry & Veterinary Medicine, 2014, 41(8): 236-241
Authors:TAN Wei  XIE Zhi-xun
Affiliation:Guangxi Key Laboratory of Animal Vaccines and Diagnosis, Guangxi Veterinary Research Institute, Nanning 530001, China
Abstract:It was found for the first time at the end of 2013 in China that avian influenza A virus subtype H10N8 could infect human beings and result in death. No such a case has been reported in other parts of the world. Similarly to H7N9, H10N8 AIV is less pathogenic in poultry. However, when an H10N8 virus infects a human being, the virus can become highly pathogenic. A person infected with an H10N8 AIV deteriorated quickly and the mortality rate is high, and H10N8 infection poses a great threat to human health. At present there are no effective means to prevent and control H10N8 AIV infection. It is currently not clear how an H10N8 AIV is transmitted to humans. There are great concerns in public whether an H10N8 AIV will cause another outbreak in humans. This article will briefly describe the characteristics of H10N8 subtype viruses and the current research on these viruses.
Keywords:avian influenza virus  gene reassortment  H10N8  H7N9  H5N1  
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