| 微卫星标记的基因组学研究进展 |
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| 引用本文： | 李明,亓小红. 微卫星标记的基因组学研究进展[J]. 天津农学院学报, 2006, 13(1): 47-51 |
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| 作者姓名： | 李明 亓小红 |
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| 作者单位： | 天津农学院,农学系,天津,300384 |
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| 基金项目： | 天津农学院科学研究发展基金计划项目“仔猪腹泻抗性特异表达基因的筛选”(20030019) |
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| 摘 要： | 微卫星标记是真核生物基因组中分布均匀、含量高的一类短重复序列。本文从微卫星标记在基因组中的分布、微卫星标记的多态性、微卫星标记的进化、微卫星标记的功能及应用等几个方面对微卫星标记的基因组学研究进展进行综述。
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| 关 键 词： | 微卫星标记 基因组学 遗传标记 重复序列 |
| 文章编号： | 1008-5394（2006）01-0047-05 |
| 收稿时间： | 2005-03-16 |
| 修稿时间： | 2005-03-16 |
Genomic Progress on Microsatellites of Eukaryotes |
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| LI Ming,QI Xiao-hong. Genomic Progress on Microsatellites of Eukaryotes[J]. Journal of Tianjin Agricultural University, 2006, 13(1): 47-51 |
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| Authors: | LI Ming QI Xiao-hong |
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| Affiliation: | Department of Agronomy, Tianjin Agricultural University, Tianjin 300384, China |
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| Abstract: | Microsatellites are simple sequence tandem repeats(SSTRs).The repeat units are generally di-,tri-,tetra-or pentanucleotides.They tend to occur in non-coding regions of the DNA although a few human genetic disorders are caused by(trinucleotide)microsatellite regions in coding regions.Microsatellites are useful genetic markers because they are locus-specific,codominant,PCR-based,highly polymorphic.They are useful at a range of scales from individual ID to fine-scale phylogenies including linkage mapping,forensic science and population genetics.The focus of this thesis is on the genomic progress of microsatellites' disperse,polymorphism,evolution,function in eukaryotic cells and their scientific applications. |
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| Keywords: | microsatellite genome genetic marker repeat sequence |
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