| 山栀子与水栀子利胆护肝作用的比较 |
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| 引用本文： | 徐伟,祁景琴.山栀子与水栀子利胆护肝作用的比较[J].湛江医学院学报,1995,13(2):107-110. |
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| 作者姓名： | 徐伟 祁景琴 |
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| 作者单位： | 中国药品生物制品检定所，广东医学院药理教研室 |
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| 摘 要： | 小鼠连续口饲山栀子水提物５天，血清总胆工素水平明显降低，并可明显低由四氯化炭，硫代乙酰胺诱发的血清谷丙转氨酶升高；大鼠连续给山栀子水提物４天，胆汁分泌量明显增加，加速注入胆红素的排泄。而口饲相同剂量水栀子水提物则无明显的上述作用。
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| 关 键 词： | 山栀子 水栀子 胆红素 谷丙转氨酶 栀子 药理学 |
A COMPARISON BETWEEN THE EFFECTS OF SHANZHIZI AND SHUIZHIZI ON BILIARY JUICE FLOW AND PROTECTION FROM LIVER INJURIES |
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| Xu Wei, Qi Jingqin, Yuan Huinan.A COMPARISON BETWEEN THE EFFECTS OF SHANZHIZI AND SHUIZHIZI ON BILIARY JUICE FLOW AND PROTECTION FROM LIVER INJURIES[J].Journal of Guangdong Medical College,1995,13(2):107-110. |
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| Authors: | Xu Wei Qi Jingqin Yuan Huinan |
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| Institution: | National Institute for the Control of Pharmaceutical and Biological Products |
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| Abstract: | Shanzhizi(Gardenia jasminodes ELLis)abstract given stomach perfusion daily dose of 7g/kg wt for five days in mice significantly decreased the total bilirubinin in serum and elevated alanine aminotransferase(ALT) induced by CCl4 and thioacetamide(TAA).Given daily dose of1.5g/kg wt for three days in rats it increased the biliary juice flow and accelerated plasma clearance of infused unconjuated bilirubin, while Shuizhizi(Gardenia jasminoides ELLis var. grandiflora) abstract was given in the same way,the action as above were not found. |
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| Keywords: | shanzhizi/drug effect shuizhizi/drug effect bilirubin SGPT rats mice |
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