| 兔胚胎释放物对去脾小鼠血小板数量的影响 |
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| 引用本文： | 郑行,马从容. 兔胚胎释放物对去脾小鼠血小板数量的影响[J]. 中国农业大学学报, 1995, 0(3): 244-250 |
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| 作者姓名： | 郑行 马从容 |
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| 作者单位： | 北京农业大学生物学院;100094; |
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| 基金项目： | 本研究为国家自然科学基金 |
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| 摘 要： | 兔2细胞期或8～16细胞期胚胎培养液立即或经冷冻、鲜冻后注入去脾小鼠体内,能异源性引起去脾小鼠血小板数量显著减少(P<0.050)。血小板激活因子受体竞争性拮抗剂海风藤酮能抑制这种作用。试验说明兔胚胎释放血小板激活因子,并引起去脾小鼠血小板的聚集。
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| 关 键 词： | 兔胚胎 去脾小鼠 血小板激活因子 海风藤酮 |
| 收稿时间： | 1995-02-24 |
Effect of Rabbit Embryo Releasing Substance on Platelet Count of Splenectomized Mice |
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| Zheng Xing Ma Congrong (College of Biology,BAU,Beijing. Effect of Rabbit Embryo Releasing Substance on Platelet Count of Splenectomized Mice[J]. Journal of China Agricultural University, 1995, 0(3): 244-250 |
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| Authors: | Zheng Xing Ma Congrong (College of Biology BAU Beijing |
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| Affiliation: | Zheng Xing Ma Congrong (College of Biology,BAU,Beijing 100094) |
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| Abstract: | Splenectomized mice were injected fresh or frozen-thawed 2-cell or 8-16-cell rabbit embryo- cultured medium.Rabbit embryo-cultured medium could cause a significant decrease(P<0.050)in platelet number of heterogeneous of splenectomized mice.Kadsurenone which is a competitive antagonist of platelet activating factor(PAF)receptor could inhibit this effect.Experiments illustrated that rabbit embryos released PAF and induced platelet aggregation of splenectomized mice. |
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| Keywords: | rabbit embryo splenectomized mouse platelet activating factor(PAF) kadsurenone |
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