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蚕类抗菌肽异源表达与应用研究进展
引用本文:马振刚,蓝希钳,周泽扬. 蚕类抗菌肽异源表达与应用研究进展[J]. 蚕学通讯, 2010, 30(2): 8-16
作者姓名:马振刚  蓝希钳  周泽扬
作者单位:1. 西南大学农业部蚕桑学重点实验室,重庆,400716
2. 西南大学农业部蚕桑学重点实验室,重庆,400716;重庆师范大学生命科学学院,重庆,400047
基金项目:重庆市自然科学基金重点项目,西南大学博士基金项目 
摘    要:蚕类抗菌肽作为昆虫抗菌肽之一,具有分子量小、热稳定性好、抗菌谱广等优点,是新世纪抗生素最理想的替代药物。目前已经成功鉴定40个家蚕抗菌肽基因,包括Cecropins、Enbo-cins、Attacins、Moricins、Gloverins、Lebocins和Defensins。本文综述了蚕类抗菌肽的家族分类、抗菌肽应用等内容,着重阐述了蚕类抗菌肽异源表达研究。

关 键 词:抗菌肽  异源表达  活性  应用

Research progress of heterologous expression and application of Antimicrobial Peptides from Silkworm,Bombyx mori
MA Zhen-gang,LAN Xi-qian,ZHOU Ze-yang. Research progress of heterologous expression and application of Antimicrobial Peptides from Silkworm,Bombyx mori[J]. Newsletter of Sericultural Science, 2010, 30(2): 8-16
Authors:MA Zhen-gang  LAN Xi-qian  ZHOU Ze-yang
Affiliation:MA Zhen-gang1,LAN Xi-qian1,ZHOU Ze-yang1,2(1.The key Sericultural Laboratory of Agricultural Ministry,Southwest University,Chongqing 400716,China,2.College of Bioscience of Chongqing Normal University,Chongqing 40047,China)
Abstract:Antimicrobial Peptides from Silkworm are an important group of ribosomally synthesized agents and they are often small in size,having good thermostability and wide antimicrobial spectrum.They are viable alternatives to conventional antibiotics.At the present time we have already obtained forty genes of Antimicrobial Peptides from Silkworm,Bombyx mori.They contained Cecropins,Enbocins,Attacins,Moricins,Gloverins,Lebocins and Defensins.Here we give a detailed presentation of its molecules structure,family cla...
Keywords:Antimicrobial peptides heterologous expression activity application  
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