| 小型猪特异性麻醉颉颃剂对小型猪肝肾功能的影响 |
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| 引用本文： | 姜胜,马昆,于世明,张娈松,谭丽娟,卢德章,马海鹍,范宏刚,王洪斌.小型猪特异性麻醉颉颃剂对小型猪肝肾功能的影响[J].中国兽医杂志,2012,48(1):18-20. |
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| 作者姓名： | 姜胜 马昆 于世明 张娈松 谭丽娟 卢德章 马海鹍 范宏刚 王洪斌 |
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| 作者单位： | 东北农业大学动物医学学院,黑龙江哈尔滨,150030 |
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| 基金项目： | 国家自然科学基金项目(30671552,30972227) |
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| 摘 要： | 为研究小型猪特异性麻醉颉颃剂对小型猪肝肾功能的影响,以复合麻醉剂(XFM)麻醉的中国试验用小型猪为试验模型,采用小型猪特异性麻醉颉颃剂进行催醒,检测催醒过程中血清谷草转氨酶(GOT)、谷丙转氨酶(GPT)、碱性磷酸酶(ALP)、尿素氮(BUN)、肌酐(CREA)的变化。结果发现:不同时间点小型猪血清中各项指标与麻醉前相比,差异不显著(P>0.05),均在生理范围内波动。表明临床剂量的XFM特异性麻醉颉颃剂对小型猪肝肾功能无明显影响。
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| 关 键 词： | 小型猪特异性麻醉颉颃剂 XFM 肝肾功能 催醒 |
Effects of the specifically antagonistic agent of XFM on liver and renal functions in miniature pigs |
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| JIANG Sheng,MA Kun,YU Shi-ming,ZHANG Luan-song,TAN Li-juan, LU De-zhang,MA Hai-kun,FAN Hong-gang,WANG Hong-bin.Effects of the specifically antagonistic agent of XFM on liver and renal functions in miniature pigs[J].Chinese Journal of Veterinary Medicine,2012,48(1):18-20. |
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| Authors: | JIANG Sheng MA Kun YU Shi-ming ZHANG Luan-song TAN Li-juan LU De-zhang MA Hai-kun FAN Hong-gang WANG Hong-bin |
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| Institution: | (College of Veterinary Medicine,Northeast Agricultural University,Harbin 150030,China) |
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| Abstract: | To study the effects of the specifically antagonistic agent of XFM on liver and renal functions in pigs,we chose Chinese experimental miniature pigs,which are anesthetized with XFM as the experimental models.This study reported the use of the specifically antagonistic agent of XFM to arouse miniature pigs and detect the changes of GOT,GPT,ALP,BUN and CREA.Results showed that differences in contents of GOT,GPT,ALP,BUN and CREA in blood serum of different time-point were not significant at P>0.05.And all the parameters fluctuated in the physiology range.It indicates that the clinical doses of the specifically antagonistic agent of XFM,has no significant effects on liver and kidney functions in miniature pigs. |
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| Keywords: | antagonistic agent XFM liver and renal functions miniature pigs |
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