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猪体细胞核移植技术及研究现状
引用本文:彭礼繁,罗光彬. 猪体细胞核移植技术及研究现状[J]. 广西农学报, 2007, 22(3): 44-47
作者姓名:彭礼繁  罗光彬
作者单位:沈阳农业大学动物胚胎工程实验室,辽宁沈阳,110161;沈阳农业大学动物胚胎工程实验室,辽宁沈阳,110161
摘    要:自2000年Polejaeva I A获得第1头克隆猪后,短短几年时间全世界已有10多例成功的报道,使得猪的体细胞核移植有了长足的发展,但目前猪的体细胞核移植效率依然低下,人们对核移植中重编程分子机理的认识知之甚少。简要综述了猪体细胞核移植近年来的研究进展,分析了猪核移植中的技术难点和影响因素。

关 键 词:体细胞核移植  激活  
文章编号:1003-4374(2007)03-0044-04
修稿时间:2007-02-15

The Development and Technology of Somatic Cell Nuclear Transfer in Pig
PENG Li-fan,LUO Guang-bin. The Development and Technology of Somatic Cell Nuclear Transfer in Pig[J]. Journal of Guangxi Agriculture, 2007, 22(3): 44-47
Authors:PENG Li-fan  LUO Guang-bin
Affiliation:Laboratory of Animal Embryo Engineering, Husbandry and veterinary college, Shenyang agriculture university, Shenyang, Liaoning 110161, China
Abstract:Since Polejaeva IA successfully got the first somatic cell nuclear transfer in pig in 2000,there have been more than ten successful examples in the world,but the whole efficiency is still very low.the molecular mechanism underlying animal cloning is not well known,In this article,we describe the recent advances of nuclear transplantation in pig,analyze the main problems limiting efficiency and effect factors.
Keywords:Somatic cell nuclear transfer Activation Swine
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