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Radiation therapy for incompletely excised grade II canine mast cell tumors
Authors:Poirier Valerie Jasmine  Adams William M  Forrest Lisa J  Green Eric M  Dubielzig Richard R  Vail David M
Institution:Department of Diagnostic Imaging and Radiation Oncology, Vetsuisse Faculty, University of Zurich, Wintherthurerstrasse 260, Zurich, 8057 Switzerland.
Abstract:Forty-five dogs with incompletely excised grade II mast cell tumors were treated with radiation using a cobalt 60 teletherapy unit (15 fractions of 3.2 Gy for a total of 48 Gy). Twenty-four of the dogs underwent prophylactic regional lymph node irradiation. Three (6.7%) dogs had tumor recurrence, two (4.4%) dogs developed metastasis, and 14 (31%) dogs developed a second cutaneous mast cell tumor. No difference in overall survival rate was observed between the dogs receiving and not receiving prophylactic irradiation of the regional lymph node.
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