| 转“大麻哈鱼”生长激素基因鲤对小鼠精子致畸性的影响 |
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| 引用本文： | 曹顶臣,耿波,梁利群,常玉梅,徐伟,郭佳祥,孙效文.转“大麻哈鱼”生长激素基因鲤对小鼠精子致畸性的影响[J].水产学杂志,2009,22(3):40-42. |
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| 作者姓名： | 曹顶臣 耿波 梁利群 常玉梅 徐伟 郭佳祥 孙效文 |
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| 作者单位： | 中国水产科学研究院黑龙江水产研究所,黑龙江,哈尔滨,150070 |
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| 基金项目： | 农业部北方鱼类生物工程育种重点开放实验室开放课题 |
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| 摘 要： | 通过用转"大麻哈鱼"生长激素基因鲤鱼的肉浆给小鼠进行灌胃,研究转基因鲤对哺乳动物精子致畸的影响.结果显示,灌注非转基因鲤鱼和转"大麻哈鱼"生长激素基因鲤不同剂量实验组,对小鼠精子的畸形率没有显著的差异.证明食用转"大麻哈鱼"生长激素基因鲤对哺乳动物的精子发生是安全的,初步为转基因鲤的食品安全评价提供了理论依据.
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| 关 键 词： | 转基因 鲤 小鼠 精子 畸形率 |
The Effect on the teratogenicity of mouse sperms fed with transgenic carps transferred salmon growth hormone gene |
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| CAO Ding-chen,GENG Bo,LIANG Li-qun,CHANG Yu-mei,XU Wei,GUO Jia-xiang,SUN Xiao-wen.The Effect on the teratogenicity of mouse sperms fed with transgenic carps transferred salmon growth hormone gene[J].Chinese Journal of Fisheries,2009,22(3):40-42. |
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| Authors: | CAO Ding-chen GENG Bo LIANG Li-qun CHANG Yu-mei XU Wei GUO Jia-xiang SUN Xiao-wen |
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| Institution: | Heilongjiang River Fisheries Research Institute;Chinese Academy of Fishery Sciences;Harbin 150070;China |
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| Abstract: | The experiment is to study the effect of the transgenic carps with GH gene of salmon on the teratogenicity of mouse sperms.The result shows that there is no distinguished difference between the experimental groups fed with different dose of common carps and transgenic carps.It proves that it is safety for the mammal spermatogenesis by feeding with transgenic carps.This experiment is also to provide theory to evaluate foods safety of transgenic carps preliminarily. |
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| Keywords: | transgene carp mouse sperm malformation rate |
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