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Clinical evaluation of an antiinflammatory and antioxidant diet effect in 30 dogs affected by chronic otitis externa: preliminary results
Authors:Alessandro Di Cerbo  Sara Centenaro  Francesca Beribè  Fulvio Laus  Matteo Cerquetella  Andrea Spaterna  Gianandrea Guidetti  Sergio Canello  Giuseppe Terrazzano
Affiliation:1.School of Specialization in Clinical Biochemistry,“G. d’Annunzio” University,Chieti,Italy;2.Research and Development Department,SANYpet S.p.a.,Padua,Italy;3.School of Biosciences and Veterinary Medicine,University of Camerino,Camerino,Italy;4.Department of Science,University of Basilicata,Potenza,Italy;5.Department of Translational Medical Sciences,University of Naples Federico II,Naples,Italy
Abstract:The aim of this evaluation study was to assess the possible role of a specific nutraceutical diet in relieving main clinical symptoms of chronic bilateral otitis externa (occlusion of ear canal, erythema, discharge quantity, and odor) in 30 adult dogs. Thirty dogs of different breeds (mean age?±?SEM; 6.03?±?0.15 years and mean weight?±?SEM; 32.01?±?1.17 Kg; 53.3 % males, 46.6 % females) with evident chronic clinical otitis symptoms were equally divided and randomly assigned to receive either the nutraceutical diet (ND group) or a standard diet (SD group) over a period of 90 days. In all cases a topical pharmacological treatment was given. The nutraceutical diet, also endowed with anti-inflammatory and antioxidant activities, significantly decreased the mean score intensity of all symptoms after 90 days of intervention (P?Malassezia pachydermatis infection which was only slightly reduced. Our investigation is one of the few evidence-based results where a commercial nutraceutical diet has been proven effective, in combination with drugs, in relieving otitis externa-related symptoms. This study opens new insights into otitis externa clinical management providing evidence of efficacy of a combined therapy with drugs and a specific nutraceutical diet.
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