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Amyloidosis in a dog: treatment with dimethylsulfoxide
Authors:L Spyridakis  S Brown  J Barsanti  E M Hardie  B Carlton
Abstract:A dog with hypoalbuminemia, proteinuria, and renal amyloidosis was treated with dimethylsulfoxide for 2 years. During a 1-year period, serum albumin concentrations increased to within normal range. The 24-hour urinary protein excretion was 5.7 g before treatment with dimethylsulfoxide. Two years after initiation of treatment, the 24-hour urinary protein excretion was 3.7 g. Removal of a testicle containing a Sertoli cell tumor and treatment of interdigital pyoderma may have been factors in the dog's clinical improvement. The only adverse effect from the dimethylsulfoxide treatment was the characteristic disagreeable odor.
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