中西医结合治疗晚期结肠癌的临床疗效

目的 探讨中西医结合治疗晚期结肠癌的临床疗效及生活质量研究。方法 选取在本院住院治疗的经病理检查确诊的晚期结肠癌患者73例，根据治疗方案随机分为中西医结合组（n=38）接受扶正消积汤联合XELOX方案（卡培他滨+奥沙利铂）治疗和西医组（n=35）单纯接受XELOX方案治疗，比较两组患者治疗后近期疗效、治疗前后中医症状积分、肿瘤标志物、免疫细胞水平以及生活质量的差异。结果 中西医结合组总的中医症状积分高于西医组（P<0.05）；中西医结合组治疗后的癌胚抗原（CEA）低于西医组和治疗前（P<0.05）；中西医结合组治疗后的CD4⁺、CD8⁺高于西医组（P<0.05），与治疗前比无差异（P>0.05）。结论 中西医结合治疗晚期结肠癌的近期疗效，降低中医症状积分，提高生活质量方面均好于单独西医治疗，且对免疫系统的影响较小。

Clinical Effect of Traditional Chinese Medicine Combined with Western Medicine on Patients with advanced Colon Cancer

Objective To investigate the clinical efficacy and life quality of patients with advanced colon cancer by traditional Chinese and Western Medicine. Methods 73 cases of advanced colon cancer patients diagnosed by pathological examination in our hospital were selected, which were randomly divided into Chinese and Western medicine (CW) group and Western medicine group. The CM group was received Fuzheng Xiaoji decoction combined with XELOX regimen (capecitabine plus oxaliplatin) treatment, and the Western medicine group was only given XELOX plan treatment. The short-term curative effect, TCM symptom score, tumor markers, immune cell level and quality of life before and after treatment between two groups were compared. Results TCM symptom score in CW group was higher than that in Western medicine group (P<0.05). Carcinoembryonic antigen (CEA) in CM group was lower than those in Western medicine group and before treatment (P<0.05). The CD4⁺ and CD8⁺ in CW group was higher than those in Western medicine group (P<0.05), there was no difference than before treatment (P>0.05). Conclusion Combination of traditional Chinese and Western medicine show better effect than western medicine alon on treatment of advanced colon cancer, which could reduce the TCM symptom score, improve the quality of life, and have little affect on the immune system.