加味痛泻要方配合穴位贴敷治疗腹泻型肠易激综合征临床观察

目的 观察加味痛泻要方配合穴位贴敷治疗腹泻型肠易激综合征（肝郁脾虚证）的临床疗效。方法 将90例腹泻型肠易激综合征（肝郁脾虚证）患者随机分为综合治疗组、中药治疗组和西药对照组，综合治疗组予加味痛泻要方口服联合穴位贴敷，中药治疗组以加味痛泻要方口服，西药对照组予马来酸曲美布汀片剂配合双歧杆菌三联活菌胶囊口服。结果 治疗后总有效率综合治疗组为93.3%，中药治疗组为80.0%，西药对照组为66.7%，综合治疗组疗效优于中药治疗组及西药对照组（P<0.05），中药治疗组优于西药对照组 （P<0.05）。3组治疗后中医证候总积分、腹痛VAS评分及单项症状积分均显著低于治疗前（P<0.05），且综合治疗组各积分低于中药治疗组及西药对照组（P<0.05），中药治疗组低于西药对照组（P<0.05）。3组在治疗中未发生不良反应。结论 加味痛泻要方配合穴位贴敷治疗腹泻型肠易激综合征，能明显改善临床症状，提高临床疗效，且无不良反应。

Clinical Effect of the Modified Tongxie-Yaofang Combined with Acupoint Application in the Treatment of Diarrhea Type Irritable Bowel Syndrome

Objective To observe the clinical effect of the modified Tongxie-Yaofang combined with acupoint application in the treatment of irritable bowel syndrome (IBS) (liver depression and spleen deficiency syndrome). Methods The 90 cases of IBS patients were randomly divided into comprehensive treatment (CT) group, Chinese medicine treatment (CMT) group and Western medicine treatment (WMT) group. The CT group were treated with the modified Tongxie-Yaofang combined with acupoint application. The CMT group were administrated with the modified Tongxie-Yaofang. The WMT group was given orally with trimebutine maleate tablets combined live combined bifidobacterium and lactobacillus capsules. Results The total effective rate of CT group was 93.33%, which was superior to the rate 80.0% of CMT group and 66.67% of WMT group (P<0.05), and the CMT group was better than the WMT group (P<0.05). After treatment, the TCM syndrome score, epigastric pain VAS score and single symptom score in three groups reduced significantly than before treatment (P<0.05). The scores of CT group were lower than the CMT group and WMT group (P<0.05, and the CMT group were lower than WMT group (P<0.05). No obvious side effects occurred in three groups. Conclusion The modified Tongxie-Yaofang combined with acupoint application could significantly improve the clinical symptoms of IBS with liver depression and spleen deficiency syndrome, which is safe, and without obvious side effect.