围绝经期非器质性失眠患者失眠严重程度与肝郁分级的相关性

目的 研究围绝经期妇女非器质性失眠严重程度（ISI）与肝郁的相互关系，为预防围绝经期非器质性失眠提供临床思路。方法 纳入围绝经期非器质性失眠妇女182例，根据朱文锋《证素辨证学》确定肝郁积分并分级，运用失眠严重程度指数量表进行失眠严重程度评估，统计分析ISI与肝郁积分的相互关系。结果 ISI在不同肝郁分级间的差异有统计学意义（F=3.209，P=0.024），且肝郁分级越高，ISI积分越高；样本总体的ISI评分与肝郁评分呈正相关（r=0.246，P=0.001）；不同肝郁分级与不同失眠严重程度呈正相关（r=0.243，P=0.001）。结论 围绝经期非器质性失眠妇女广泛存在不同程度的肝郁，且肝郁越严重，失眠程度越重。心理因素肝郁可诱发失眠，并且加重失眠的严重程度。

Relationship Between Insomnia Severity and Liver Depression in Perimenopausal Women with Non-Organic Insomnia

Objective To study the interrelationship between insomnia severity (ISI) and liver depression in perimenopausal women with non-organic insomnia, and to provide clinical thought for prevention and treatment of the non-organic insomnia. Methods The 182 cases of perimenopausal women with non-organic insomnia were collected. The severity of insomnia was assessed according to Insomnia Severity Index Scale. The interrelationship between ISI and liver depression was analyzed statistically. Results The difference of ISI in different grade of liver depression was statistically significant (F=3.209, P=0.024), and the higher grade of liver depression with higher ISI integral (r=0.246, P=0.001). The ISI score of overrall sample was positively correlated with liver depression (r=0.243, P=0.001). Conclusion The perimenopausal women with non-organic insomnia has different degree of liver depression, and the more serious degree of liver depression with more serious of insomnia. The psychological factors type of depression could cause insomnia, and increase the severity of insomnia.