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非洲猪瘟疫苗研究进展
引用本文:李运娜,王冠,贾皓,戴晓光,苏胜杰,王旭红. 非洲猪瘟疫苗研究进展[J]. 畜牧与饲料科学, 2022, 43(1): 115-118. DOI: 10.12160/j.issn.1672-5190.2022.01.019
作者姓名:李运娜  王冠  贾皓  戴晓光  苏胜杰  王旭红
作者单位:1.内蒙古自治区动物疫病预防控制中心,内蒙古 呼和浩特 010010; 2.内蒙古自治区农畜产品质量安全中心,内蒙古 呼和浩特 010010
摘    要:非洲猪瘟(African swine fever,ASF)是由非洲猪瘟病毒(African swine fever virus,ASFV)引起的家猪和野猪的急性、出血性传染病,强毒株感染猪的致死率接近100%,给养猪业造成巨大经济损失。ASFV在猪群中可以快速有效传播,在环境中可稳定存在,为ASF的防控带来了挑战。研究人员一直致力于ASF疫苗的研究,迄今为止,仍没有有效的疫苗投入市场。综述了ASF灭活疫苗、减毒活疫苗、亚单位疫苗、DNA疫苗、病毒活载体疫苗的研究情况,以期为ASF疫苗的有效研发提供参考。

关 键 词:非洲猪瘟  疫苗  研发进展  
收稿时间:2021-12-10

Research Progress of African Swine Fever Vaccine
LI Yun-na,WANG Guan,JIA Hao,DAI Xiao-guang,SU Sheng-jie,WANG Xu-hong. Research Progress of African Swine Fever Vaccine[J]. Animal Husbandry and Feed Science, 2022, 43(1): 115-118. DOI: 10.12160/j.issn.1672-5190.2022.01.019
Authors:LI Yun-na  WANG Guan  JIA Hao  DAI Xiao-guang  SU Sheng-jie  WANG Xu-hong
Affiliation:1. Inner Mongolia Center for Animal Disease Prevention and Control,Hohhot 010010,China; 2. Inner Mongolia Center for Quality and Safety of Agriculture and Livestock Products,Hohhot 010010,China
Abstract:African swine fever (ASF) is an acute and hemorrhagic infectious disease caused by the African swine fever virus (ASFV) in farmed pigs and wild boars. Pigs infected with a highly virulent ASFV strain have a near 100% mortality rate, resulting in massive economic losses for the pig industry. ASFV spreads quickly and effectively in pigs and persists in the environment, posing challenges for prevention and control of ASF. The development of ASF vaccine has been a priority for researchers. There hasn′t been a successful vaccine on the market yet. In order to give a reference for successful research and development of ASF vaccine, this paper reviewed the current research status of ASF inactivated vaccine, live attenuated vaccine, subunit vaccine, DNA vaccine, and live viral vector vaccine.
Keywords:African swine fever  vaccine  research and development progress
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