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Phylogenetic analysis of recent classical swine fever virus (CSFV) isolates from Assam, India |
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| Authors: | Dilip Kumar SarmaNiranjan Mishra Stefan VilcekKatherukamem Rajukumar Sthita Pragnya BeheraRam Kumar Nema Pooja DubeyShiv Chandra Dubey |
| Institution: | a Assam Agricultural University, Khanapara, Guwahati 781022, Assam, India b High Security Animal Disease Laboratory, Indian Veterinary Research Institute, Anand Nagar, Bhopal 462021, Madhya Pradesh, India c Department of Infectious Diseases and Epizootiology, University of Veterinary Medicine, Komensky 73, Kosice, Slovak Republic |
| Abstract: | Classical swine fever (CSF), a highly contagious viral disease of pigs, is endemic in India. As there is no information concerning the accurate genetic typing of classical swine fever virus (CSFV) isolates in India, 16 CSF viruses isolated during 2005-2007 from domestic pigs in different districts of Assam were typed in 5′ UTR (150 nucleotides). To confirm the genetic typing results and to study the genetic variability, selected viruses were also analyzed in E2 (190 nt) and NS5B gene (409 nt) regions. Phylogenetic analysis revealed that all the 16 CSFV isolates analyzed belonged to group 1 and subgroup 1.1 in contrast to the situation in other Asian countries. Additionally, analysis in E2 and NS5B region placed the Indian isolates in a clearly separated clade within subgroup 1.1. The results suggest that subgroup 1.1 CSF viruses are currently circulating in India, which is important for epidemiology and control of CSF. |
| Keywords: | Classical swine fever virus E2 India NS5B Phylogenetic analysis 5&prime UTR |
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