Diagnosis and management of Wegener's granulomatosis in a dog |
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Authors: | Krug William Marretta Sandra Manfra de Lorimier Louis-Philippe White Dean K Borst Luke |
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Institution: | Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, 61802, USA. wvkrug@ncsu.edu |
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Abstract: | A four-year-old maele/neutered mixed-breed dog was prsented for severe, multifocal, proliferative gingivitis. Histopathologic examination of incisional biopsies supported a diagnosis of Wegener's granulomatosis, an autoimmune vasculitis previously unreported in the veterinary literature. Diagnostic investigations for infectious, neoplastic, or other inflammatory conditions all provided negative results. Management with a combination of immunosuppressive agents resulted in complete resolution and remission of the presenting lesions and associated clinical signs. |
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