Plasmodium chloroquine resistance and the search for a replacement antimalarial drug |
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Authors: | Wellems Thomas E |
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Institution: | Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA. tew@helix.nih.gov |
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Abstract: | Genetic and biochemical research is providing new information on the mechanism of chloroquine resistance. Drug discovery initiatives are finding new leads that have favorable pharmaceutical properties and efficacy against chloroquine-resistant malaria. |
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