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| 猪繁殖与呼吸综合征病毒免疫生物学最新研究进展 | |
| 引用本文： | 耿海东,徐钰,解林红,卢艳敏,张红梅.猪繁殖与呼吸综合征病毒免疫生物学最新研究进展[J].野生动物,2012,33(4):236-245. |
| 作者姓名： | 耿海东 徐钰 解林红 卢艳敏 张红梅 |
| 作者单位： | 1. 国家林业局野生动物疫源疫病监测总站,沈阳,110034 2. 河北衡水学院生命科学系,衡水,053000 3. 山东菏泽学院生命科学系,菏泽,274015 |
| 摘 要： | 猪繁殖与呼吸综合征病毒是对养猪业危害最严重的病原之一,猪和野猪是其唯一的自然宿主,野猪可呈隐性携带传播病毒,在该病流行中的作用需要给予重视。近20 a来,有关免疫方面的研究比较多,尽管疫苗已经应用很多年,但是它却不能提供全面的保护作用。本文着重从病毒受体、抗病毒先天性免疫反应、病毒的免疫调节以及获得性免疫反应的特征与作用等病毒的免疫生物学方面展开讨论,并就未来的研究提出一些建议,希望对推动野猪养殖业的健康发展提供一定的帮助。 |
| 关 键 词： | 猪繁殖与呼吸综合征病毒 疫苗 先天性免疫反应 免疫调节 获得性免疫反应 |
Research Progress in Porcine Reproductive and Respiratory Syndrome Virus Immunobiology |
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| Authors: | Geng Haidong Xu Yu Xie Linhong Lu Yanmin Zhang Hongmei |
| Institution: | 1.The General Monitoring Station for Wildlife-borne Infectious Diseases,SFA,Shenyang,110034,China; 2.College of Life Science,Hengshui University,Hengshui,Hebei,053000,China; 3.Department of Life Sciences,Heze College,Heze,Shandong,274015,China)) |
| Abstract: | Porcine reproductive and respiratory syndrome virus（PRRSV）is one of the most costly pathogens for the swine industry. Domestic swine and wild boar are the only natural hosts of PRRSV.The potential for PRRSV epidemic requires attention. In the most recent two decades,much has been learned about the immunobiology of PRRSV.Although vaccines are available, they do not provide full and universal protection against PRRSV infection.We review and discuss current issues in PRRSV virus immunobiology,including：roles of viral receptors,innate immune responses to the virus,regulation of the immune response by PRRSV,and the characteristics and roles of adaptive immunity.We offer guidance for future research to promote healthy development of the wild boar farming industry. |
| Keywords: | PRRSV Vaccine Innate immune response Immune regulation Adaptive immunity |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |