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杀虫活性多肽研究进展
引用本文:叶德兴,周源琳,张怡萌,陈黛妮,杨新玲. 杀虫活性多肽研究进展[J]. 农药学学报, 2022, 24(5): 962-981. DOI: 10.16801/j.issn.1008-7303.2022.0114
作者姓名:叶德兴  周源琳  张怡萌  陈黛妮  杨新玲
作者单位:1.中国农业大学 理学院 应用化学系 农药创新研究中心,北京 100193
基金项目:国家自然科学基金 (21877126).
摘    要:传统杀虫剂在防治害虫、保障农作物丰收等方面做出了卓越贡献,但是由于其化学性质以及不合理使用,对环境也带来了一些负面影响。因此,以环境友好为前提,寻找结构独特、性能优异以及绿色安全的杀虫剂尤为迫切。多肽是由多个氨基酸通过肽键连接而成,也是蛋白质降解而成的中间产物,在生命过程中具有重要作用。近年来,杀虫活性多肽因其新颖的作用机制、优异的活性、理想的环境相容性而成为农药领域一颗冉冉升起的新星。本文主要从来源于动物、植物和微生物的杀虫活性多肽角度出发,综述了其近年来的研究进展及应用,并对未来的研究趋势进行了展望。

关 键 词:多肽  动物毒素  昆虫神经肽  植物环肽  微生物多肽  杀虫活性肽  研究进展
收稿时间:2022-08-24

Research progress of insecticidal peptides: a review
Affiliation:1.Innovation Center of Pesticide Research, Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China
Abstract:Traditional insecticides have made remarkable contributions to pest control and crop harvest, but bring about some adverse impacts on environment due to their chemical properties and unreasonable use. Consequently, it is particularly urgent to discover pesticides with unique structure, excellent performance and green safety on the premise of ecological friendliness. Polypeptide is composed of multiple amino acids connected by peptide bonds, and also is an intermediate product of protein degradation and plays a significant role in the life process. In recent years, insecticidal peptides have become a rising star in the field of pesticides thanks to their novel mechanism, excellent activity and ideal environmental compatibility. This review mainly summarizes the research progress and application of insecticidal peptides from animals, plants and micro-organisms, and prospect for future research trends.
Keywords:
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