Toxic nodular goitre in the cat |
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| Authors: | MARGARETHE HOENIG MICHAEL H GOLDSCHMIDT† DUNCAN C FERGUSON‡ KAARON KOCH&#; MICHAEL J EYMONTT&#; |
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| Institution: | *Departments of Clinical Studies University of Pennsylvania Philadelphia, PA 19104, U.S.A.;†Departments of Pathobiology School of Veterinary Medicine The Department of Medicine University of Pennsylvania Philadelphia, PA 19104, U.S.A.;‡Section of Endocrinology The Department of Medicine School of Veterinary Medicine The Department of Medicine University of Pennsylvania Philadelphia, PA 19104, U.S.A.;‖Department of Radiology Section of Nuclear Medicine School of Medicine, University of Pennsylvania Philadelphia, PA 19104, U.S.A. |
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| Abstract: | Hyperthyroidism was diagnosed in 24 aged cats and was characterized by palpable enlargement of the thyroid gland, high circulating levels of thyroid hormones, increased thyroidal uptake of 123I, and abnormal uptake and distribution of activity on thyroid scintiscans. Unilateral or bilateral thyroidectomy was performed in all cats and resulted in remission of signs in all but one case. The histological diagnosis was adenomatous hyperplasia in 23 cats and adenocarcinoma in one. Serum thyroid hormone concentrations decreased to normal or subnormal levels within 24 hours after complete removal of functioning thyroid nodules. Hypothyroidism occurred postoperatively in 16 of the 24 cats. Presumed hypoparathyroidism and hypocalcaemia occurred in 6 cases. |
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