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Medication‐related osteonecrosis of the jaw after long‐term bisphosphonate treatment in a cat
Authors:Melinda J. Larson  Ashley B. Oakes  Ember Epperson  Dennis J. Chew
Abstract:A 12‐year‐old, neutered female, domestic medium hair cat was evaluated for a nonhealing, oral mucosal ulceration. The cat had a history of idiopathic hypercalcemia that had been treated with a bisphosphonate for 41 months. Oral examination identified exposed maxillary bone adjacent to a previous extraction site. Histopathology of the exposed bone and associated mucosa was most consistent with medication‐related osteonecrosis of the jaw. Treatment involved both medical and surgical interventions. Oral mucosal healing occurred after 6 months of treatment.
Keywords:alendronate  aminobisphosphonate  bisphosphonate‐related osteonecrosis of the jaw  hypercalcemia  osteomyelitis  pamidronate
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