La_2O_3-黄酮纳米复合材料的制备及其抗氧化与抑菌性能研究

黄酮类化合物具有较好的抗菌性能,而稀土氧化物具有较强的清除羟基自由基能力。本研究利用硅烷偶联剂(KH560)的偶联接枝作用,将黄酮接枝在纳米La2O3表面,制备La2O3-黄酮复合纳米材料,并进行清除羟基自由基和体外抑菌(大肠杆菌、金黄色葡萄球菌)试验。结果表明,该复合材料具有较强的清除羟基自由基能力和抑制细菌生长能力。细胞毒性试验结果表明,黄酮的存在使该材料具有较低的细胞毒性和较好的细胞相容性。La2O3-黄酮纳米复合材料有望应用于食品保鲜添加剂和医学等领域。

Study on Synthesis and Antioxidation, Antibacterial Action of La2O3-Flavonoid Nano-compoiste

Flavonoids have excellent ability of antibacterial, and the rare earth oxides have the strong ability to remove hydroxyl radicals. The La2O3/Flavonoid nano-composite was prepared using the grafting method of KH560, and the tests of hydroxyl radical scavenging and antibacterial activity in vitro (Escherichia coli, Staphylococcus aureus) were carried out. The results showed that, the composite material had strong ability to remove hydroxyl radicals and inhibit bacterial growth. Results of cell toxicity test showed that, flavonoid made this material had lower cytotoxicity and better cellular compatibility. La2O3/Flavonoid nano-composite was expected to be applied in the field of food additives and medicine.