| DNA疫苗研究进展 |
| |
| 引用本文： | 王昌青,杨兵.DNA疫苗研究进展[J].中国畜牧兽医,2009,36(12):143-146. |
| |
| 作者姓名： | 王昌青 杨兵 |
| |
| 作者单位： | (北京市农林科学院畜牧兽医研究所， 北京 100097) |
| |
| 摘 要： | 核酸疫苗作为第3代新型疫苗,其制作简单、经济安全、易于贮存运输等优点已日益引起广泛重视。复制型或称“自杀性”DNA 疫苗是基于常规的DNA疫苗和自主复制型RNA疫苗而发展起来的一种新型疫苗，具备高度的安全稳定性和对外源基因的高效表达。作者简述了常规DNA疫苗的发展过程和复制型DNA疫苗的研究进展。
|
| 关 键 词： | 疫苗 DNA 复制子 甲病毒 |
Study on the Development of DNA Vaccine |
| |
| WANG Chang-qing,YANG Bing.Study on the Development of DNA Vaccine[J].China Animal Husbandry & Veterinary Medicine,2009,36(12):143-146. |
| |
| Authors: | WANG Chang-qing YANG Bing |
| |
| Institution: | （Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China） |
| |
| Abstract: | As the third generation of vaccine,DNA vaccine seems to be advantageous over classic immunization with which was used safely,economically and conveniently.Replicative DNA vaccine(or suicidal DNA vaccine) was based on conventional DNA vaccine and RNA self-replicon-based vaccine,it not only has high stability and security,but also has high level of heterologous gene expression.In this article,the development of classic DNA vaccine and construction,biological mechanism,advantage and some new advances in resear... |
| |
| Keywords: | DNA |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国畜牧兽医》浏览原始摘要信息 |
| 点击此处可从《中国畜牧兽医》下载免费的PDF全文 |
|
