| 细菌耐药性产生的分子机制与耐药基因的快速检测方法 |
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| 引用本文： | 崔晓文,张秀英.细菌耐药性产生的分子机制与耐药基因的快速检测方法[J].中国兽药杂志,2004,38(9):30-32. |
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| 作者姓名： | 崔晓文 张秀英 |
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| 作者单位： | 东北农业大学动物医学院,黑龙江,哈尔滨,150030 |
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| 摘 要： | 细菌产生耐药性成为临床治疗感染性疾病失败的主要原因.本文综述了由自发基因突变和获得性细菌耐药性产生的分子机制,及目前常用的快速检测细菌耐药基因的方法,包括聚合酶链反应-单链构象多态性分析(PCR-SSCP)、质粒指纹图谱分析和PCR-限制性片段长度多肽性分析(PCR-RFLP).
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| 关 键 词： | 细菌耐药性 分子机制 基因 检测方法 |
| 文章编号： | 1002-1280(2004)09-0030-03 |
| 修稿时间： | 2004年3月22日 |
Molecular mechanism of bacterial resistance to antibiotics and rapid methods for detecting antimicrobial resistant gene |
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| CUI Xiao-wen,ZHANG Xiu-ying.Molecular mechanism of bacterial resistance to antibiotics and rapid methods for detecting antimicrobial resistant gene[J].Chinese Journal of Veterinary Drug,2004,38(9):30-32. |
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| Authors: | CUI Xiao-wen ZHANG Xiu-ying |
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| Abstract: | It is considered that the bacterial resistance to antibiotics is one of the major causes of failure to (controlling) infectious (diseases). In this paper, the current situation and mechanism of bacterial resistance to (antibiotics) and a series of methods for detecting antimicrobial resistant gene were described. |
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| Keywords: | bacterial resistance molecular mechanism gene detecting method |
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