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Antibody responses to Toxoplasma gondii antigens in aqueous and cerebrospinal fluids of cats infected with T. gondii and FIV. |
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| Authors: | Dah-Sheng Lin Dwight D. Bowman Richard H. Jacobson |
| Affiliation: | 1 Department of Veterinary Medicine, National Taiwan University, 142 Chou-San Road, Taipei, Taiwan 2 Department of Microbiology, Immunology and Parasitology College of Veterinary Medicine, Cornell University, Ithaca, NY 14853-6401, U.S.A. 3 Diagnostic Laboratory, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853-6401, U.S.A. |
| Abstract: | Antibodies to antigens of Toxoplasma gondii were measured in the aqueous and cerebrospinal fluid (CSF) of 16 specific-pathogen free kittens experimentally infected with feline immunodeficiency virus (FIV), T. gondii, or both pathogens. The results indicated that all cats infected with T. gondii had antibody responses to antigens of T. gondii in both aqueous fluids and CSF. Co-infection with FIV did not affect antibody levels. Aqueous fluids from eyes of cats with toxoplasmic retinochoroiditis did not necessarily have higher antibody levels than those from eyes without lesions. Antibodies to T. gondii were also detected in the CSF of two cats from whose brains no parasites were isolated by in vivo mouse inoculation. Total IgG did not increase significantly in the aqueous fluids and CSF of cats infected with T. gondii whether or not they were also infected with FIV. |
| Keywords: | AIDS eyes brain retinochoroiditis immunodiffusion CSF IgG cats Toxoplasma gondii FIVAuthor Keywords: SIDA oeil cerveau retinochoriodites immunoglobine G chat liquide cérébrospinale Toxoplasma gondii FIV |
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