| 抗猪附红细胞体药物体外筛选试验 |
| |
| 引用本文： | 王 婧,蔺红玲,汪 芳,张继瑜. 抗猪附红细胞体药物体外筛选试验[J]. 西北农业学报, 2010, 19(7): 25-29 |
| |
| 作者姓名： | 王 婧 蔺红玲 汪 芳 张继瑜 |
| |
| 作者单位： | 1. 甘肃农业大学,动物医学院,兰州,730070;中国农业科学院,兰州畜牧与兽药研究所,新兽药重点开放实验室,兰州,730050
2. 甘肃农业大学,动物医学院,兰州,730070 |
| |
| 基金项目： | 国家高技术研究发展计划(863计划)重大课题，中央级公益性科研院所基本科研业务费专项资金项目 |
| |
| 摘 要： | 为筛选抗猪附红细胞体的有效药物,采用体外培养方法,对常用的治疗药物以及兰州畜牧与兽药研究所新兽药重点开放实验室研制的青蒿琥酯纳米乳进行体外筛选。通过镜检计数红细胞胞染虫率判断其作用效果,并进一步筛选部分有效药物作用质量浓度。结果表明,在体外盐酸吖啶黄效果最好,当质量浓度为500μg/mL时能起到较好的抗猪附红细胞体的作用,且在有效质量浓度范围内对红细胞的影响较轻微;其次为青蒿琥酯纳米乳,但培养过程中红细胞有崩解现象;强力霉素,贝尼尔对猪附红细胞体有一定作用;其他药物无作用。
|
| 关 键 词： | 猪附红细胞体 药物 红细胞染虫率 |
Selection of Effective Drugs Resistant to Eperythrozoon suis in Vitro |
| |
| WANG Jing,LIN Honglin,WANG Fang and ZHANG Jiyu. Selection of Effective Drugs Resistant to Eperythrozoon suis in Vitro[J]. Acta Agriculturae Boreali-occidentalis Sinica, 2010, 19(7): 25-29 |
| |
| Authors: | WANG Jing LIN Honglin WANG Fang ZHANG Jiyu |
| |
| Affiliation: | WANG Jing1,2,LIN Honglin1,WANG Fang1 and ZHANG Jiyu1(1.College of Veterinary Medicine,Gansu Agricultural University,Lanzhou 730070,China,2.Key Laboratory of New Animal Medicine Project,Lanzhou Institute of Animal &Veterinary Pharmaceutics Sciences,Chinese Academyof Agricultural Sciences,Lanzhou 730050,China) |
| |
| Abstract: | In order to select the effective medicines to treat eperythrozoonosis,we had screen some drugs which usually used to cure the eperythrozoonosis in clinical,and artesunate nano-emulsion produced by our own lab.The effects of the drugs were judged by examination of the blood smears and calculation the infection rate of erythrocyte according the microscopic,then screening the concentration of some effective drugs.The result of the experiment indicated that the effect of flavacridin hydrochloride was the best w... |
| |
| Keywords: | Eperythrozoon suis Drug Infection rate of erythrocyte |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《西北农业学报》浏览原始摘要信息 |
|
点击此处可从《西北农业学报》下载全文 |
|
