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榆黄菇菌丝体多糖提取及抗肿瘤活性研究
引用本文:辛晓林,黄清荣,史亚丽. 榆黄菇菌丝体多糖提取及抗肿瘤活性研究[J]. 安徽农业科学, 2006, 34(2): 256-256,258
作者姓名:辛晓林  黄清荣  史亚丽
作者单位:烟台师范学院生命科学学院,山东,烟台,264025;烟台师范学院生命科学学院,山东,烟台,264025;烟台师范学院生命科学学院,山东,烟台,264025
基金项目:烟台师范学院校科研和教改项目
摘    要:液体发酵榆黄菇,从菌丝体中提取粗多糖,研究其体内抗肿瘤活性。用0.2、0.4、0.8 g/kg3个剂量组对荷S180小鼠进行灌胃,结果发现:榆黄菇菌丝体粗多糖得率为2.99%,低、中、高3个剂量组对肿瘤的抑制率分别为30.14%、41.73%和48.87%,同时能提高荷瘤小鼠的胸腺指数和脾指数。榆黄菇菌丝体多糖具有明显的抗肿瘤活性。

关 键 词:榆黄菇  菌丝体  多糖  抗肿瘤
文章编号:0517-6611(2006)02-0256-01
收稿时间:2005-09-23
修稿时间:2005-09-23

Isolation of Polysaccharide from Submerged Fermentation Liquid of Pleurotus Cirtinopileatus and its Antitumor Activity
XIN Xiao-lin et al. Isolation of Polysaccharide from Submerged Fermentation Liquid of Pleurotus Cirtinopileatus and its Antitumor Activity[J]. Journal of Anhui Agricultural Sciences, 2006, 34(2): 256-256,258
Authors:XIN Xiao-lin et al
Affiliation:Department of Biology, Yantai Normal University, Yantai, Shandong 264025
Abstract:Polysaccharide was extracted from submerged mycelium of Pleurotus Cirtinopileatus for the research on its anti-tumor activity.After the tumor S180-bearing mice were given with 0.2 g/kg,0.4 g/kg and 0.8 g/kg of the polysaccharide liquid down the stomach,the results showed that the rate of polysaccharide gained from submerged mycelium of Pleurotus Cirtinopileatus was 2.99 %.And the tumor inhibition rate of the three different assays was 30.14 %,41.73 % and 48.87 %.They can all advance the thymus and lienal index of the tumor-bearing mice at the same time.So it was concluded that the polysaccharide from submerged mycelium of Pleurotus Cirtinopileatus obtained a prominent antitumor activity.
Keywords:Pleurotus Cirtinopileatus  Mycelium  Polysaccharide  Anti-tumor
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