QUANTITATIVE99mTc-PERTECHNETATE THYROID SCINTIGRAPHY IN NORMAL BEAGLES |
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Authors: | William H Adams DVM Gregory B Daniel DVM MS Mark G Petersen DVEM Karen Young BS |
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Institution: | Department of Small animal Clinical Sciences, University of Tennessee, College of Veterinary Medicine, Knoxville, Tennessee 37901-1071.;Department of Comparative Medicine, University of Tennessee, College of Veterinary Medicine, Knoxville, Tennessee 37901-1071. |
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Abstract: | This study was done to investigate the validity of published canine thyroid/salivary (TS) rations of approximately i in normal dogs and to detemine thyroid uptak of 99mTc-pertechnetate (pertechnetate) measured as percent uptake of injected dose. These parameters were evaluated in 13 Beagle dogs over a 4 hour period. Mean ± standard deviation (SD) and median T/S ratios of 1.2 ± 0.3 and 1.1 were essentially the same at twenty minutes and 1 hour. T/S Values ranged from 0.9 to 2.2 at 20minutes and from 0.8 to 2.4 at 1 hour. T/S ratio values progressively declined over the subsequent time intervals with mean ± SD and median values of 0.6 ± 0.2 and 0.6, respectively, measured at 4 hour. The mean with a rang of 0.28% to 0.90%. The mean ± SD time interval from injection of pertechanetate to maximum uptake within the thyroid gland was 160 ± 55 minutes with a range 31–240 minutes. The data derived from this study of normal dogs may be useful in the evaluation of dogs with thyroidal diseases including hypthyroidism |
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