丙硫苯咪唑混合饲料对猪旋毛虫病疗效的研究

本研究的目的是筛选丙硫苯咪唑治疗猪旋毛虫病最佳效果的剂型、剂量,用药途径和疗程.经不同剂量的混悬水乳剂、油乳剂肌肉注射和粉剂加水胃投、药物混入饲料饲喂等途径给药,共治疗人工感染猪旋毛虫病患猪62头.结果以丙硫苯咪唑300ppm混合饲料饲喂10天的效果最佳,杀虫率为100%.肌幼虫被药物杀死后,在一段时间内呈现死亡肌幼虫包囊,虫体钙化,钙化虫体崩解吸收由增生的结缔组织代替——机化.最后由肌纤维再生修复受损伤的肌组织,整个过程半年左右.

A STUDY ON THE EFFECT OF ALBENDAZOLE MIXED FEED ON TREATMENT OF SWINE TRICHINOSIS

The optimal dosage, administering route and form of albendazole for treating swine trichinosis were screened. The drug was given to the pigs infected with trichineila spira-lis in different doses and forms, p. o. or i. m. administration. Of the 62 pigs given the drug, 14 received albendazole as an additive at the concentration 300ppm were free from T.spiralis. It was shown that the parasiticidal rate was 100%. The best period of treatment was 10 days. The histological change of the host muscular tissues was also discussed. The cyst which surrounds the killed T.spiralis muscle larva was firstly calcified, and then the worm. Some time later, the calcified worm was organized by connective tissues. The muscular tissues injured by the larvas were repaired with regenerated muscular fiber cells at last. These processes were completed about 6 months.