Penicillin-induced hemolytic anemia and acute hepatic failure following treatment of tetanus in a horse |
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| Authors: | D L Step J T Blue S G Dill |
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| Institution: | Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University Ithaca 14853. |
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| Abstract: | Acute, severe hemolytic anemia occurred in a horse being treated for tetanus with intravenous penicillin and tetanus antitoxin. During treatment, the horse developed a positive direct antiglobulin test and a high titer (maximum 1:1024) of IgG anti-penicillin antibody. The horse recovered from the tetanus and penicillin induced hemolytic anemia, but later developed acute hepatic failure, probably resulting from the administration of equine origin tetanus antitoxin. |
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