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乳牛产后期生理性免疫状态的研究
引用本文:黄群山,戴承胜,刘宇.乳牛产后期生理性免疫状态的研究[J].中国兽医科技,2005,35(10):816-819.
作者姓名:黄群山  戴承胜  刘宇
作者单位:华南农业大学兽医学院,广东广州510642
基金项目:广东自然科学基金资助项目(32273).致谢本试验是在暨南大学生命科学学院器官移植与免疫中心实验室完成的,在试验过程中,得到了曾耀英教授、江逊博士、王通老师、肇静娴老师以及黄秀艳硕士生的热情帮助,谨致以衷心感谢!
摘    要:为了研究乳牛在产后期的生理性免疫状态,检测了产后期乳牛淋巴细胞及其亚群数量和淋巴细胞增殖活化功能及其变化。结果发现,乳牛淋巴细胞及其亚群数量和淋巴细胞增殖活化功能在分娩后第1d最低,然后表现出缓慢上升的总体趋势。CD3细胞数在产后第15d低于产后第1d,到产后第30d时达到最高值;CD4细胞数一直多于CD8细胞数;CD21细胞数在产后第15d时达到最高值,以后缓慢下降;淋巴细胞的增殖活化能力在产后第30d最高,未观察到淋巴细胞有明显的凋亡和增生现象。结果表明,乳牛免疫状态在产后第1d最低,以后逐渐升高,第15d时细胞免疫最低而体液免疫最高,第30d时细胞免疫最强。

关 键 词:产后期  免疫状态  乳牛
文章编号:1000-6419(2005)10-0816-04
收稿时间:2005-08-16

Study on physiologic immunity status of dairy cows during puerperal period
HUANG Qun-shan, DAI Cheng-sheng, LIU Yu.Study on physiologic immunity status of dairy cows during puerperal period[J].Chinese Journal of Veterinary Science and Technology,2005,35(10):816-819.
Authors:HUANG Qun-shan  DAI Cheng-sheng  LIU Yu
Institution:College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China
Abstract:The populations of lymphocytes expressing CD3, CD4, CD8 and CD21, and ConA stimulated proliferation of lymphocytes were examined in three Holstein cows during the puerperal period. The proportion and the proliferation of lymphocytes were at lowest level on day 1 post-parturition and generally exhibited a gradual increase in the puerperal period. The proportion of CD21 lymphocyte and proliferation of lymphocytes reached highest value on day 15 and 30 post-parturition respectively. The percentage of CD3 lymphocyte was fluctuated with lowest point on day 15 and highest point on day 30 post-parturition.
Keywords:puerperal period  immunity status  dairy cow
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