Excretion of DDT residues into milk of the Indian buffalo,Bubalus bubalis (L.) after oral and dermal exposure |
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Authors: | Rajinder L Kalra Ram P Chawla Balbir S Joia Mewa S Tiwana |
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Abstract: | Three groups of buffaloes were fed with 20, 100 and 400 mg of p,p′-DDT in their daily rations. The DDT residues in the milk fat of the treated animals showed an initial rapid rise but soon attained a dose-dependent equilibrium. The transfer coefficient of DDT residues in milk at ‘plateau’ levels showed an average value of about 12%. Half-life values for the rate of decline of DDT residues during the post-dosing period were computed according to a two-open-compartment model. Dermal application of p,p′-DDT to buffaloes also resulted in excretion of a significant amount of its residues in milk. TDE was the predominant compound present in milk when buffaloes had ingested p,p′-DDT, whilst p,p′-DDT itself was present in greater quantity than its metabolites when animals were treated dermally. |
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