| 鸡球虫的同工酶的研究 |
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| 引用本文： | 甘德培,汪明.鸡球虫的同工酶的研究[J].中国农业大学学报,1998(Z2). |
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| 作者姓名： | 甘德培 汪明 |
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| 作者单位： | 中国农业大学动物医学院;100094; |
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| 基金项目： | 国家自然科学基金项目39670562 |
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| 摘 要： | 将三对抗不同药物的 Eimeria tenella 虫株(氯嗪苯乙氰抗性株与盐霉素抗性株、氯嗪苯乙氰抗性株与氯羟吡啶抗性株、氯嗪苯乙氰抗性株与拉沙里菌素抗性株)分别等量混合感染不给药的鸡只,获得各自的杂交一代 F_1.再用 F_1感染饲喂双重药物的鸡只,通过双重药物的筛选,分别获得了各自的 E.tenella抗药性重组株 F_2~(ds),F_2~(de),F_2~(dl).这3株抗药性重组株在 F_2代中所占比例分别为:19.9%,36.5%,26.7%,重组株对相关的两种药产生了完全的抗药性.试验结果还显示,重组株的致病力与 E.tenella 敏感株无明显差异.
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| 关 键 词： | 柔嫩艾美耳球虫 抗药性 杂交 |
Genetic Transfer of Drug Resistance in Eimeria tenella |
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| Gan Depei Wang Ming.Genetic Transfer of Drug Resistance in Eimeria tenella[J].Journal of China Agricultural University,1998(Z2). |
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| Authors: | Gan Depei Wang Ming |
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| Institution: | Gan Depei Wang Ming (College of Vet.Medicine,CAH,Beijing 100094) |
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| Abstract: | A series of experiments were described in which three pairs of drug-resistant strains of E.tenella(diclazuril resistant strain and salinomycin resistant strain,diclazuril resistant strain and lasalocid resistant strain,clopidol resistant strain and diclazuril resis- tant strain)were passaged together in untreated chicks respectively.The resultant oocysts were then inoculated into chicks treated with the both drugs.Resistance to the both drugs was apparent as shown by the oocyst output of chicks,which receiv... |
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| Keywords: | E tenella drug-resistance transference |
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