|
|||||
|
|
Histamine production by transplantable argyrophilic gastric carcinoid of Praomys (Mastomys) natalensis |
|
| Authors: | S Hosoda W Nakamura K C Snell H L Stewart |
| Abstract: | A transplantable argyrophilic gastric carcinoid of Praomys (Mastomys) natalensis contained appreciable amounts of histamine. Dialyzed, microsome-free supernatant of tumor tissue produced definite amounts of histamine in the presence of L-histidine and pyridoxal phosphate. These findings may relate to hypersecretion of gastric acid and formation of multiple ulcers in the stomach and duodenum of Mastomys bearing carcinoids. |
| Keywords: | |