The liver in systemic disease. An innocent bystander

The role of the liver in maintaining the health and function of other organs is frequently described in pathophysiologic terms. A large volume of information has been gleaned on the biochemistry and physiology of the "primary" hepatic diseases. In the dog, there is a paucity of information about the chemical events essential to the viability of normal liver cells and, more specifically, the mechanisms by which diseases of other organs secondarily affect the liver.