Extrinsic regulation of domestic animal-derived myogenic satellite cells II |
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| Authors: | RP Rhoads ME Fernyhough X Liu DC McFarland SG Velleman GJ Hausman MV Dodson |
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| Institution: | 1. Department of Animal Sciences, University of Arizona, Tucson, AZ 85719, United States;2. The Hartz Mountain Corporation, Secaucus, NJ 07094, United States;3. Department of Animal and Range Sciences, South Dakota State University, Brookings, SD 57007, United States;4. The Ohio State University/OARDC, Wooster, OH 44691, United States;5. USDA-ARS, Richard B. Russell Agricultural Research Station, Athens, GA 30604, United States;6. Department of Animal Sciences, Washington State University, Pullman, WA 99164, United States |
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| Abstract: | The existence of myogenic satellite cells was reported some 47 years ago, and, since that time, satellite cell research has flourished. So much new information is generated (daily) on these cells that it can be difficult for individuals to keep abreast of important issues related to their activation and proliferation, the modulation of the activity of other cell types, the differentiation of the cells to facilitate normal skeletal muscle growth and development, or to the repair of damaged myofibers. The intent of this review is to summarize new information about the extrinsic regulation of myogenic satellite cells and to provide specific mechanisms involved in altering satellite cell physiology. Where possible, examples from agriculturally important animals are used for illustrative purposes. |
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| Keywords: | Satellite cells Extrinsic regulation Extracellular matrix Steroids Growth factors |
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