Serum levels of stanniocalcin-1 in Holstein heifers and cows |
| |
| Authors: | G Tremblay L Delbecchi MC Loiselle C Ster GF Wagner BG Talbot P Lacasse |
| |
| Institution: | 1. Département de Biologie, Faculté des Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada J1K 2R1;2. Dairy and Swine Research and Development Centre, Agriculture and Agri-Food Canada, P.O. Box 90 STN Lennoxville, Sherbrooke, Quebec, Canada J1M 1Z3;3. Department of Physiology and Pharmacology, Faculty of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada N6A 5C1 |
| |
| Abstract: | Stanniocalcin-1 is a hormone that possesses both paracrine and endocrine functions and has recently been identified in mammals. While paracrine functions have been determined for several organs, the role of circulating stanniocalcin-1 in cattle is still unclear but, observations in mice and cows suggest that stanniocalcin-1 plays a role in both gestation and lactation. The changes in serum stanniocalcin-1 content in different physiological states have never been evaluated in ruminants. We measured stanniocalcin-1 levels in sera from cattle ranging in age from post-weaned calves to 17-month-old heifers and in sera from cows during lactation and pregnancy. Our results indicate that the blood concentration of stanniocalcin-1 is increased by pregnancy, but not by lactation. The highest levels of stanniocalcin-1 were found in young calves and during the non-lactating period preceding calving. This suggests that stanniocalcin-1 is important for gestation and the preparation of the mammary gland for lactation. |
| |
| Keywords: | Dry period Pregnancy Lactation Stanniocalcin-1 Bovine |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
