两种开胸术法建立犬右心衰模型的对比

通过4例胸骨正中手术通路和8例左胸侧壁手术通路,连接心电极导线至犬右心室,并与起搏器连接,维持高频率起搏3周,构建实验性心衰模型,观察两种开胸术的切口愈合情况、以及起搏前后临床表现。结果表明,通过开胸术给犬安装、连接快频率右心室起搏器,成功构建犬右心室心衰病理模型。左胸侧壁手术通路比胸骨正中手术通路更适合。

Comparison of two thoracic surgical approaches on the construction of canine right heart failure model

To establish canine heart failure model,12 dogs were implanted and connected a rapid pacemaker by thoracotomy.The surgical approach was at the middle of manubrium of sternum in 4 dogs and on the left thoracic wall in 8 dogs.The dogs were underwent rapid pacing at 200 bpm for 3 weeks and were observed the wound healing as well as clinical symptoms pre-and post-onset rapid pacing in these two surgical approaches.As pacing prolonged,canine right heart failure model was established successfully.In the operation,the approach on the left thoracic wall was better than that at the middle of manubrium of sternum.