Hypoglycemic and antidiabetic activities on the stem bark aqueous and ethanol extracts of Musanga cecropioides in normal and alloxan-induced diabetic rats |
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Authors: | Adeneye A A Ajagbonna O P Ayodele O W |
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Institution: | Department of Pharmacology, Lagos State University of Medicine, P.M.B. 21266, Ikeja, Lagos State, Nigeria. adeneye2001@yahoo.com |
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Abstract: | Daily oral administration of the aqueous and ethanolic extracts of Musanga cecropioides stem bark in normal and diabetic rats at doses of 250, 500 and 1000 mg/kg/day, for 14 days significantly lowered the fasting plasma glucose levels in normal and alloxan-induced diabetic rats in dose-dependent fashion. The ethanol extract induced more significant antidiabetic effect than the aqueous extract. |
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Keywords: | Musanga cecropioides Hypoglycemic Antidiabetic Stem bark |
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