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国产三氯苯咪唑驱除山羊肝片形吸虫效果试验
引用本文:陶建平,许金俊,刘建明,盛红兵. 国产三氯苯咪唑驱除山羊肝片形吸虫效果试验[J]. 动物医学进展, 2002, 23(6): 82-83,92
作者姓名:陶建平  许金俊  刘建明  盛红兵
作者单位:1. 扬州大学畜牧兽医学院,江苏扬州,225009
2. 张家港市畜牧兽医站,江苏张家港市,215600
基金项目:陕西省汉江药业股份有限公司资助
摘    要:以国产三氯苯咪唑对自然感染肝片形吸虫的山羊进行了驱虫试验,并以硝氯酚为药物对照。结果表明,三氯本咪唑5mg/kg体重的剂量对肝片形吸虫成虫和童虫的驱虫率分别为99.3%和92.9%,驱净率为75%;三氯苯咪唑10mg/kg体重的剂量对肝片形吸虫成虫和童虫的驱虫率均为100%,驱净率为100%;硝氯酚5mg/kg体重剂量对肝片形吸虫成虫驱虫率为100%,但对童虫的仅为74.3%,而驱净率仅为60%。在整个试验期间试验羊均无不良反应。

关 键 词:驱虫效果 国产三氯苯咪唑 山羊 肝片形吸虫
文章编号:1007-5038(2002)06-0082-03

Efficacy of Triclabendazole against Fasciola hepatica in Naturally Infected Goats
TAO Jian ping ,XU Jin jun ,LIU Jian ming ,SHENG Hong bing. Efficacy of Triclabendazole against Fasciola hepatica in Naturally Infected Goats[J]. Progress In Veterinary Medicine, 2002, 23(6): 82-83,92
Authors:TAO Jian ping   XU Jin jun   LIU Jian ming   SHENG Hong bing
Affiliation:TAO Jian ping 1,XU Jin jun 1,LIU Jian ming 2,SHENG Hong bing 2
Abstract:The efficacy of triclabendazole made in China was tested againstFasciola hepatica in naturally infected goats and compared with that of niclofolan. At 10 mg/kg, triclabendazole was 100% effective in eliminating both immature and adult flukes. At a lower dose of 5 mg/kg, triclabendazole was 92.9% and 99.3% efficient against immature and adult flukes respectively. Niclofolan at 5 mg/kg showed 100% efficiency against adult fluks, but its effect on immature flukes was 74.3%. Clinical toxic reactions were not observed in the treat goats. Triclabendazole was shown here to be safe and effective, and 10 mg/kg body weight at single oral does rate was recommended.
Keywords:triclabendazole  efficacy  Fasciola hepatica  goat
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