| T细胞的发育分化及胸腺激素的作用 |
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| 引用本文： | 计慧琴,王丙云,陈志胜,江青艳.T细胞的发育分化及胸腺激素的作用[J].动物医学进展,2005,26(4):47-50. |
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| 作者姓名： | 计慧琴 王丙云 陈志胜 江青艳 |
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| 作者单位： | 佛山科学技术学院动物医学系,广东佛山,528231;华南农业大学动物科学学院,广东广州,510642 |
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| 摘 要： | 胸腺既是免疫器官,又是内分泌器官。胸腺是T淋巴细胞发育、分化和成熟的场所。原胸腺细胞,经过前胸腺细胞、CD4-CD8-双阴性细胞、CD4 CD8 双阳性细胞以及CD4 CD8-或CD4- CD8 两个单阳性胸腺细胞亚群共5 个阶段,发育分化为成熟的T淋巴细胞。胸腺微环境是T淋巴细胞发育分化的重要条件。胸腺上皮细胞分泌产生的胸腺激素在T淋巴细胞发育分化过程中起重要作用。文章着重综述了T淋巴细胞发育分化过程及胸腺激素的生化性质和生物学功能。
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| 关 键 词： | T细胞 发育分化 胸腺激素 |
| 文章编号： | 1007-5038(2005)04-0047-04 |
| 修稿时间： | 2004年10月8日 |
Development and Differentiation of T Cell and Functions of Thymus Hormone |
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| JI Hui-qin,WANG Bing-yun,CHEN Zhi-sheng,JIANG Qing-yan.Development and Differentiation of T Cell and Functions of Thymus Hormone[J].Progress In Veterinary Medicine,2005,26(4):47-50. |
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| Authors: | JI Hui-qin WANG Bing-yun CHEN Zhi-sheng JIANG Qing-yan |
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| Abstract: | Thymus which is an immune and endocrine organ is a place of T cell development, differentiation and maturation. The stages of thymocyte development and differentiation include prothymocyte, prethymocyte, CD4~(-)CD8~(-) thymocyte, CD4~( )CD8~( )thymocyte, CD4~(-)CD8~( ) thymocyte and CD4~( )CD8~(-) thymocyte. The thymus microenviroment is very important for T cell development and differentiation. The thymus hormones secreted by thymus epithelial cell plays a important role during T cell development and differentiation. This paper reviewed courses of T cell development, differentiation and roles of thymus hormones. |
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| Keywords: | T cell development and differentiation thymus hormones |
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