Evaluation of the the effectiveness of a newly developed tissue-inactivated vaccine against rabies using the NIH test |
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Authors: | V Vrzal Z Cupera J Chumela L Zatloukal |
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Institution: | Bioveta, Ivanovice na Hané. |
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Abstract: | NIH test was used to verify 12 operation batches of the newly developed inactivated tissue vaccine against rabies. The number of international units per 1 cm3 of vaccine was determined by the volumetric method. The number of international units (I.U.) per 1 cm3 of the newly developed vaccines ranged from 1.08 I.U. to 2.59 I.U. per cm3. The average value of all the 12 batches tested is 1.52 I.U. per cm3. The average value of international units in the vaccination dose for dogs is 4.57. All the tested operation batches of the newly developed vaccines met the activity standard recommended by the World Health Organization for veterinary vaccines of this type. |
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