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不同给药途径的姬松茸多糖对鼠急性肝损伤的保护效应及其抗氧化作用的研究
引用本文:马吉飞,段县平,马文芝,郑东虎,李天俊.不同给药途径的姬松茸多糖对鼠急性肝损伤的保护效应及其抗氧化作用的研究[J].猪业科学,2004,21(4):42-43.
作者姓名:马吉飞  段县平  马文芝  郑东虎  李天俊
作者单位:天津农学院动物科学系,天津,300384;天津农学院动物科学系,天津,300384;天津农学院动物科学系,天津,300384;天津农学院动物科学系,天津,300384;天津农学院动物科学系,天津,300384
基金项目:天津市高等学校科技发展基金项目20031705,天津农学院科技发展基金项目2003
摘    要:分别通过灌胃、皮下注射的方法,给予小鼠姬松茸多糖灭菌溶液,连续7d。然后经四氯化碳染毒12h后,采血并制备肝组织匀浆液进行GPT、GOT活性及SOD、MDA含量的检测。结果表明:用姬松茸多糖灌胃比皮下注射能更快、更有效的保护肝损伤;而SOD活性及MDA含量未见有统计学差异。

关 键 词:姬松茸多糖  四氯化碳    肝保护
文章编号:1008-9381(2004)04-0042-02
修稿时间:2004年1月16日

Protective Effect and Anti-oxidation of ABM Polysaccharide By Different Ways on Liver Injury in Mice
Ma Ji-fei,Duan Xian-ping,Ma Wen-yi,Zheng Dong-hu,Li Tian-jun.Protective Effect and Anti-oxidation of ABM Polysaccharide By Different Ways on Liver Injury in Mice[J].Swine Industry Science,2004,21(4):42-43.
Authors:Ma Ji-fei  Duan Xian-ping  Ma Wen-yi  Zheng Dong-hu  Li Tian-jun
Abstract:Mice was given ABM polysaccharide by oral injection and hypodermic injection for 7days prior to CCl4 injury. Serum glutamate-pyruvate transaminase (GPT) and glutamic-oxaloacetic transaminase (GOT) activities were determined 12 h after CCl4 injury. The activitie of liver SOD and the content of liver MDA were also detected.. Conclusion: ABM polysaccharide by oral injection had a better protective action against hepatic injury than by hypodermic injection,but ABM polysaccharide showed no evident effect on the activitie of liver SOD.
Keywords:ABM polysaccharide  CCl4  mice  hepatic protection
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