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| 拷贝数变异及其在奶牛育种中的研究现状 | |
| 引用本文： | 吴晓平,刘林,刘文娇,孙东晓.拷贝数变异及其在奶牛育种中的研究现状[J].中国奶牛,2012(11):2-6. |
| 作者姓名： | 吴晓平 刘林 刘文娇 孙东晓 |
| 作者单位： | 1. 中国农业大学动物科技学院,北京,100193 2. 北京奶牛中心,北京,100192 3. 中国奶业协会,北京,100192 |
| 摘 要： | 拷贝数变异(copy number variation,CNV)作为结构变异的一种新形式,在品种多样性、生物进化和疾病相关性等研究中起着重要作用。本文主要介绍了CNV的相关概念、分类、作用机制等,并对近年来的研究进行了总结;简单介绍了目前检测CNV的常用技术和CNV在奶牛育种中的研究现状;阐述了当前CNV研究进展缓慢的部分原因,并对其与疾病、生物进化和物种多样性相关性研究的前景进行了一些展望。 |
| 关 键 词： | 结构变异 拷贝数变异 奶牛育种 |
Copy Number Variations and Its Current Progress in Dairy Breeding |
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| WU Xiao-ping,LIU Lin,LIU Wen-jiao,WANG Peng,SUN Dong-xiao.Copy Number Variations and Its Current Progress in Dairy Breeding[J].China Dairy Cattle,2012(11):2-6. | |
| Authors: | WU Xiao-ping LIU Lin LIU Wen-jiao WANG Peng SUN Dong-xiao |
| Institution: | 1.College of Animal Science and Technology, China Agricultural University, Beijing 100193; 2. Beijing Dairy Cattle Center, Beijing 100192; 3. Dairy Association of China, Beijing 100192) |
| Abstract: | Copy number variation （CNV） has recently gained considerable mterest as source of structure varmuon likely playing important role in researching phenotypic diversity, evolution and disease study. Much efforts has been made in the identification and mapping regions varying in copy numbers among normal individuals in human, using bioinformatics or hybridization based methods. The study introduced briefly concept, classify and mechanism of CNV, and gave a sum-up about recently study. This article pointed out the problem in CNV study and concerned more CNV in dairy breeding. |
| Keywords: | Structural variation Copy number variations Dairy breeding |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |