Histopathologic study of long-bone growth plates confirms the basset hound as an osteochondrodysplastic breed |
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| Authors: | Simn Martínez Raúl Fajardo Jesús Valds Raúl Ulloa-Arvizu and Rogelio Alonso |
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| Institution: | Centro de Investigaciones y de Estudios Avanzados en Salud Animal, Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca Edo. México. simonmc@uaemex.mx |
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| Abstract: | Osteochondrodysplasias are caused by abnormal development and growth of cartilage and bone. These abnormalities have been reported in both humans and animals with dwarfism. The basset hound is considered a breed with a disproportionate prevalence of dwarfism, the cause of which is unknown. To determine the type of osteochondrodysplasia in this breed, we analyzed histologically the growth plates from the long bones of a basset hound and a Doberman pinscher, both 2 mo old. Tissue was fixed in 4% paraformaldehyde, embedded in paraffin, sectioned at 5 microm, stained with hematoxylin and eosin, and analyzed by light microscopy. Our results suggest that by this method the basset hound can be defined only as a breed having osteochondrodysplasia due to a primary cartilage problem in the growth plate. |
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